CHARACTERIZATION OF AVIAN INFLUENZA-VIRUSES - DESIGNATION OF A NEWLY RECOGNIZED HEMAGGLUTININ

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 54  (5) , 555-560
Abstract
Studies with specific antisera to the hemagglutinin and neuraminidase antigens of all the influenza A subtypes showed that A/turkey/Wisconsin/66 influenza virus, originally included in the Hav6 subtype, did not react in hemagglutinin inhibition or immunodiffusion tests with antisera to Hav6. It was proposed that A/turkey/Wisconsin/66 be placed in a new subtype designated Hav9. The neuraminidase antigens of the Hav6 subtype were further characterized and were shown to be N1, N2, Neq2 and Nav5 subtypes. Hav6 influenza viruses isolated from turkeys over a 11 yr period showed little antigenic drift. The hemagglutinin and neuraminidase of A/shearwater/Australia/72 (Hav6Nav5) were identical with those of a virus isolated 8 yr previously from a turkey in California (USA): A/turkey/California/64 (Hav6Nav5).