Fetal Development of Nonspecific Esterases and Alkaline Phosphatases Activities in the Small Intestine of the Man

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Abstract
The activity of the soluble non-specific esterase (substrate [beta]-naphtyl-acetate) in the proximal and distal third of human small intestine does not change between 7 and 22 postconceptional weeks; the activity of the ileum is always higher. Electrophoresis showed the presence of 1 anodic and 2 cathodic fractions, which move together with "slow moving gamma globulins". Soluble alkaline phosphatase activity increases steadily in the jejunum. In the ileum first an increase between 7 and 11 postconceptional weeks was observed and later activity decreased. In the age group of 8.5-10.5 fetal weeks no proxi-modistal difference was found later except in one fetus (22-weeks-old) the activity in the ileum was higher.