Low-Substituted Hydroxypropylcellulose as a Sustained-Drug Release Matrix Base or Disintegrant Depending on Its Particle Size and Loading in Formulation
- 1 January 1993
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 10 (3) , 351-355
- https://doi.org/10.1023/a:1018975919598
Abstract
Tablets of acetaminophen as a model drug were prepared with low-substituted hydroxypropylcellulose (L-HPC) of various particle sizes at various loadings in the formulation. Drug release into an...Keywords
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