Length of the Flagellar Hook and the Capacity of the Type III Export Apparatus
- 23 March 2001
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 291 (5512) , 2411-2413
- https://doi.org/10.1126/science.1058366
Abstract
Length determination in biology generally uses molecular rulers. The hook, a part of the flagellum of motile bacteria, has an invariant length. Here, we examined hook length and found that it was determined not by molecular rulers but probably by the amount of subunit protein secreted by the flagellar export apparatus. The export apparatus shares common features with the type III virulence-factor secretion machinery and thus may be used more widely in length determination of structures other than flagella.Keywords
This publication has 27 references indexed in Scilit:
- FliK, the protein responsible for flagellar hook length control in Salmonella, is exported during hook assemblyMolecular Microbiology, 1999
- Supramolecular Structure of the Salmonella typhimurium Type III Protein Secretion SystemScience, 1998
- Effect of cellular level of fliK on flagellar hook and filament assembly in Salmonella typhimuriumJournal of Molecular Biology, 1998
- Kinetic Analysis of the Growth Rate of the Flagellar Hook in Salmonella typhimurium by the Population Balance MethodBiophysical Journal, 1998
- Geometry of the Flagellar Motor in the Cytoplasmic Membrane ofSalmonella typhimuriumas Determined by Stereo-photogrammetry of Quick-freeze Deep-etch Replica ImagesJournal of Molecular Biology, 1996
- Flagellar assembly in Salmonella typhimuriumMolecular Microbiology, 1996
- Isolation, Characterization and Structure of Bacterial Flagellar Motors Containing the Switch ComplexJournal of Molecular Biology, 1994
- Morphological pathway of flagellar assembly in Salmonella typhimuriumJournal of Molecular Biology, 1992
- The cytoplasmic component of the bacterial flagellar motor.Proceedings of the National Academy of Sciences, 1992
- Stoichiometric analysis of the flagellar hook-(basal-body) complex of Salmonella typhimuriumJournal of Molecular Biology, 1990