Nonpeptide glycoprotein IIB/IIIA inhibitors. 12. Potent and orally active centrally constrained thieno[2,3-c]pyridones
- 19 November 1996
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 6 (22) , 2771-2776
- https://doi.org/10.1016/s0960-894x(96)00511-2
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Non-peptide glycoprotein IIb/IIIa inhibitors. 9. Centrally constrained alpha-sulfonamides are useful tools for exploring platelet receptor functionBioorganic & Medicinal Chemistry Letters, 1996
- Tailoring echistatin to possess higher affinity for integrin αIIbβ3FEBS Letters, 1996
- Studies Directed Toward the Regioselective Carboxylation of the 4-Oxo-4,5,6,7-Tetrahydrothieno-[3,2-C]pyridine Ring SystemSynthetic Communications, 1996
- Non-peptide fibrinogen receptor antagonists. 3. design and discovery of a centrally constrained inhibitorBioorganic & Medicinal Chemistry Letters, 1994
- Non-Peptide Fibrinogen Receptor Antagonists. 2. Optimization of a Tyrosine Template as a Mimic for Arg-Gly-AspJournal of Medicinal Chemistry, 1994
- MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man.Circulation, 1993
- Structural studies of potent constrained RGD peptidesJournal of the American Chemical Society, 1992
- Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitorsJournal of Medicinal Chemistry, 1992
- The Pathogenesis of Coronary Artery Disease and the Acute Coronary SyndromesNew England Journal of Medicine, 1992
- Platelet receptor recognition domains on the .alpha. chain of human fibrinogen: structure-function analysisBiochemistry, 1989