Before the work of Redfern1 in 1851, it was thought that hyaline cartilage possessed little or no power of regeneration. Since that time the experimental studies on hyaline cartilage have shown that it possesses this property, but the investigators cannot agree as to the exact method by which it is brought about. The object of this communication is to review the more significant papers in the literature on the regeneration of hyaline cartilage in joints, ribs and ears, and to present the results of experiments on the injury and healing of hyaline cartilage in the joints of dogs. The literature of this country contains no experimental reports of such work in joints. Most of the reports have come from England, Germany, France and Italy. Hunter2 published an article, "The Structure and Disease of Articulating Cartilage," in which he said, "From Hippocrates to the present age it is universally