FRIEDLÄNDER'S BACILLUS MENINGITIS WITH REPORT OF CASE TREATED UNSUCCESSFULLY WITH SULFADIAZINE

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Abstract
Freidlander''s bacillus meningitis is not only rare but was almost invariably fatal prior to sulfonamide therapy, with which cures have been reported. Infants, and adults past middle age, generally with some debilitating systemic condition are most susceptible. Meningitis caused by Friedlander''s bacillus is generally secondary to some primary focus, most often in the middle ear, mastoid or sinus but also in the gastrointestinal, respiratory, genitourinary tracts and elsewhere. The author''s case. a six months old infant, first developed enteritis then broncho-pneumonia and meningitis. Although adequately treated with sulfadiazine, he failed to recover. At autopsy, findings included catarrhal ileocolitis, bilateral bronchopneumonia and diffuse lepto-meningitis with clear identification of Fried-lander''s bacillus as the causative organism.