Peritoneal-plasma barrier

Abstract
Intraperitoneal chemotherapy has been described as a therapeutic option in the management of a variety of malignancies that occur primarily in a locoregional manner [1]. Potential benefits of this technique may occur in tumors principally confined to the peritoneal cavity (gastrointestinal malignancies and ovarian carcinoma) [2,3]. Theoretically, the use of intraperitoneal drug could eliminate local tumor spread as a mechanism of cancer recurrence both in the abdomen and in the pelvis.