Serum Complement and Chronic Glomerulonephritis

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Abstract
Biopsy studies are differentiating several types of glomerular injury in patients with primary persistent glomerulonephritis, and in a majority serial measurements show serum complement levels to be normal rather than low (as tradition holds). These findings suggest that mechanisms other than, or in addition to, the antigen-antibody reaction may be responsible for the condition classically known as “chronic nephritis.”

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