Hormone Replacement Therapy and Dry Eye Syndrome

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Abstract
Dry eye syndrome, or keratoconjunctivitis sicca, damages the ocular surface and can cause debilitating symptoms of dryness and irritation, which may result in psychological comorbidity and reduced work capacity.1-4 Dry eye syndrome is associated with an enhanced risk of corneal infection, and, when severe, can cause permanent visual impairment.2,3 Treatments for dry eye syndrome are generally costly and inadequate, and many patients are unable to find satisfactory relief from their symptoms.5 Finally, dry eye syndrome accounts for a substantial burden on the health care system,5 comprising one of the leading causes of patient visits to both ophthalmologists and optometrists.2

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