T1 and t2 of ferritin at different field strengths: effect on mri
- 1 October 1992
- journal article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 27 (2) , 368-374
- https://doi.org/10.1002/mrm.1910270218
Abstract
Nuclear magnetic relaxation times T1 and T2 were measured in ferritin solutions at field strengths from 0.04 to 1.5 T.T1 was relatively constant, but 1/T2 increased linearly with field strength, in agreement with earlier MRI observations in the monkey brain. This finding supports the theory that ferritin is responsible for T2 shortening in brain nuclei containing iron. The linear dependence of 1/T2 on magnetic field is unique and not explained by present theories of the magnetic properties of ferritin.Keywords
This publication has 18 references indexed in Scilit:
- Role of iron and ferritin in MR imaging of the brain: a study in primates at different field strengths.Radiology, 1990
- Does signal-attenuation on high-field T2-weighted MRI of the brain reflect regional cerebral iron deposition? Observations on the relationship between regional cerebral water proton T2 values and iron levels.Journal of Neurology, Neurosurgery & Psychiatry, 1989
- Mechanisms responsible for the MR appearance and evolution of intracranial hemorrhage.RadioGraphics, 1988
- Magnetic resonance imaging of stationary blood: A reviewMedical Physics, 1987
- Transverse relaxation of solvent protons induced by magnetized spheres: Application to ferritin, erythrocytes, and magnetiteMagnetic Resonance in Medicine, 1987
- Siderosomal ferritin. The missing link between ferritin and haemosiderin?Biochemical Journal, 1987
- Relaxometry of ferritin solutions and the influence of the Fe3+ core ionsMagnetic Resonance in Medicine, 1986
- Multiple system atrophy (Shy-Drager syndrome): MR imaging.Radiology, 1986
- Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron.Radiology, 1986
- Nuclear magnetic resonance imaging of the liver: initial experienceAmerican Journal of Roentgenology, 1982