Abstract
Polymorphonuclear leukocyte (PMN) function may be an important determinant in resistance against periodontitis. Since tobacco smoke may interfere with PMN function, the chemotactic response of PMN to serum and saliva was studied in smokers and nonsmokers and again in the same subjects after all smoked one cigarette. The assay used in this investigation appeared to be sensitive enough to detect some differences between polymorphonuclear leukocyte chemotaxis in some individuals. However, no effect of smoking of the ability of the cells to migrate of the ability of serum or serum or saliva to stimulate such migration was detected.