Immunoglobulin deposits in skin in systemic lupus erythematosus
Open Access
- 1 January 1975
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 18 (1) , 77-82
- https://doi.org/10.1002/art.1780180115
Abstract
Immunoglobulin deposits in the dermal-epidermal junction of clinically normal skin from patients with SLE were eluted by acid buffer. The eluates contained antinuclear and antibasement membrane antibody activities. The anti-BM antibody reacted with skin and esophageal but not glomerular basement membrane. Enzymatic studies indicated that the antibody reacted with carbohydrate moeities in the basement membrane. The anti-BM antibody was not present in corresponding sera of SLE patients.Keywords
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