DETERMINANTS OF NORMAL TIMED VITAL CAPACITY

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Abstract
The records of 387 normal subjects chosen from 4,342 subjects studied were analyzed to determine the normal values for the forced expiratory volume per cent (FEV%) as well as the determinants of FEV1%. When males were compared with females and when young people were compared with older ones, no consistent significant difference was found in the FEV1%. However, when analyzed in terms of the forced vital capacity (FVC), and by age and sex, keeping the FVC constant, it was demonstrated that FEV1% not only is not a constant for all normal subjects, but is a function of age, sex, and FVC. Feminity and aging tend to lower the FEV1%, although lowering of the FVC tends to raise it. It is suggested that normal values for FEV1% take these effects into account.

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