Histochemical Evidence of Steroid Metabolism in the Human Genital Ridge
- 1 July 1966
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 26 (7) , 738-741
- https://doi.org/10.1210/jcem-26-7-738
Abstract
3/3-, 16)3- and 17(3-Hydroxysteroid dehydrogenases have been demonstrated in genital ridge mesenchyme of a 14 mm human fetus. Traces of enzymic activity were noted when 3a-hydroxysteroids were used as substrates, but no reaction was seen with 11[BETA]-, 16[al[ha]- and 20[beta]-hydroxysteroids. These findings point to possible steroid metabolism in the genital ridge mesenchyme; this metabolism may be relevant to primordial germ cell migration and proliferation.This publication has 2 references indexed in Scilit:
- Histochemical observations on the germ cells of human embryosThe Anatomical Record, 1953
- Observational and experimental evidences relating to the origin and differentiation of the definitive germ cells in miceJournal of Experimental Zoology, 1943