Phototoxic eruptions due to doxycycline-a dose-related phenomenon

Publisher Website
Google Scholar
Abstract
The tetracycline group of antibiotics still remains the most successful oral treatment for acne. They are relatively free from side-effects apart from the occasional gastrointestinal upset or vaginal candidosis. Rarer side-effects include drug rashes,1 pigmentation with minocycline2 and a light-sensitive eruption with doxycycline.3,4 The incidence of light-sensitive rashes with doxycycline at a dose of 100 mg daily, is in the order of 3%.5 Acne does not always respond to conventional regimens of antibiotics and higher dosages may be required.6 We report a highly significant incidence of light-sensitive eruptions in patients receiving doxycycline at a daily dose of 150 mg or above.

This publication has 9 references indexed in Scilit: