Phenylethylamine in Paranoid Chronic Schizophrenia
- 26 October 1979
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 206 (4417) , 470-471
- https://doi.org/10.1126/science.504988
Abstract
Phenylethylamine (PEA) is an endogenous amine that is structurally and pharmacologically related to amphetamine. Urinary PEA excretion is significantly higher in paranoid chronic schizophrenics than in nonparanoid chronic schizophrenics and normal controls. Diet, hospitalization, and medication do not account for differences in PEA concentrations. These findings offer some indication that PEA may be an endogenous amphetamine.Keywords
This publication has 13 references indexed in Scilit:
- Tolerance development to a disruptive effect of ?-phenylethylamine (PEA) on a learned behavior in ratsPsychopharmacology, 1979
- MASS FRAGMENTOGRAPHY OF PHENYLETHYLAMINE, m‐ AND p‐TYRAMINE AND RELATED AMINES IN PLASMA, CEREBROSPINAL FLUID, URINE, AND BRAINJournal of Neurochemistry, 1979
- The effect of urinary pH and flow rate on monoamine outputClinica Chimica Acta; International Journal of Clinical Chemistry, 1978
- A fluorometric assay for β-phenylethylamine in human urineClinica Chimica Acta; International Journal of Clinical Chemistry, 1977
- Chronic phenylethylamine stereotypy in rats: A new animal model for schizophrenia?Life Sciences, 1977
- Substrate-typic changes of platelet monoamine oxidase activity in sub-types of schizophreniaArchiv Fur Psychiatrie Und Nervenkrankheiten, 1977
- Response : Dopamine Receptors and Average Clinical DosesScience, 1976
- Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic DrugsScience, 1976
- Separation, detection and quantitative, analysis of urinary β-phenylethylamineJournal of Chromatography A, 1971
- Stereotyped activities produced by amphetamine in several animal species and manPsychopharmacology, 1967