In squamous cell carcinoma of the vulva, overexpression of p53 is a late event and neither p53 nor mdm2 expression is a useful marker to predict lymph node metastases

This publication has 34 references indexed in Scilit:

• MDM-2 protein is expressed in different layers of normal human skin
  Oncogene, 1997
• Mitotic Count, Nuclear Atypia, and Immunohistochemical Determination of Ki-67, c-myc, p21-ras, c-erbB2, and p53 Expression in Granulosa Cell Tumors of the Ovary: Mitotic Count and Ki-67 Are Indicators of Poor Prognosis
  Gynecologic Oncology, 1996
• Presence and persistence of HPV infection and p53 mutation in cancer of the cervix uteri and the vulva
  International Journal of Cancer, 1995
• mdm2 Gene Amplification and Overexpression in Non-Small Cell Lung Carcinomas with Accumulation of the p53 Protein in the Absence of p53 Gene Mutations
  Diagnostic Molecular Pathology, 1995
• Immunohistochemically detectable p53 and mdm-2 oncoprotein expression in colorectal carcinoma: prognostic significance
  Molecular Pathology, 1995
• MDM2 gene amplification in human breast cancer
  European Journal Of Cancer, 1994
• The p53-mdm-2 autoregulatory feedback loop.
  Genes & Development, 1993
• Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma
  The Lancet, 1992
• p53, guardian of the genome
  Nature, 1992
• The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
  Cell, 1992