CORTICAL ATROPHY IN SCHIZOPHRENIA AND MANIA - A COMPARATIVE CT STUDY

  • 1 January 1982
    • journal article
    • research article
    • Vol. 43  (11) , 439-441
Abstract
Schizophrenic (55), manic (24) and control subjects (27), all males aged 20-45 yr, were examined for structural brain abnormalities with computerized tomography (CT) scans. Both manic and schizophrenic samples had significantly larger ventricles than the control group. Cerebral atrophy was more frequent in schizophrenia, while cerebellar atrophy was more frequent in mania. An association between increased ventricular size and cerebellar atrophy was found in mania but not in schizophrenia. Cerbral atrophy was not associated with ventricular enlargement in either disorder. Implications of these findings are discussed.

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