Enhanced Surfaces for Endothelial Cell Seeding

Abstract
Silver negative ions (Ag) were implanted to polystyrene (PS) and tissue culture polystyrene (TCPS) by using neutral and ionized alkaline bombardment-type heavy negative ion sources, NIABNIS. Surface property and biocompatibility of Ag-implanted TCPS and PS were investigated. Enhanced growth of vascular endothelial cells was observed on Ag-implanted TCPS at a dose of 1016 ions·cm−2 at an ion energy of 10 keV and Ag-implanted (at ca. 1015 ions·cm−2 dose and 10 keV energy) PS region. As a result of Ag-implantation, PS and TCPS surfaces were considered to be more hydrophobic and to be more hydrophilic, respectively.

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