PROTEIN COAGULATION AND ITS REVERSAL
Open Access
- 19 March 1930
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 13 (4) , 469-476
- https://doi.org/10.1085/jgp.13.4.469
Abstract
1. By a procedure involving the use of acid acetone hemoglobin may be rapidly separated into a precipitate of denatured globin and an acetone solution of heme. 2. By neutralization procedures the denatured globin may be largely converted into a soluble, apparently native form which can combine with heme to form hemoglobin. 3. The heme may be obtained in acetone-free, slightly alkaline solution without the use of strong alkali which may modify the heme.Keywords
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- On hæmochromogen and the relation of protein to the properties of the hæmoglobin moleculeThe Journal of Physiology, 1925