Enzyme-catalysed baeyer–villiger oxidations of some substituted bicyclo[3.2.0]heptanones

Abstract
The ketones 1 and 4 are oxidized to γ-lactones 2 and 5 with low enantioselectivity by both Acinetobacter sp. NCIB 9871 and Pseudomonas sp. NCIB 9872; in contrast the ketones 7 and 10 are biotransformed to products 8/9 and 11 respectively of very high optical purity.

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