Bone Mineral Density in Children and Adolescent Females Treated with High Doses of L·Thyroxine

Abstract
Single-photon absorptiometry was used to assess forearm bone mineral content (BMC) at a proximal site (PBMC) and at a more distal site (DBMC) of the non-dominant distal forearm in 20 children and adolescent females taking high doses of L-thyroxine (120 µg/m2/day) for a period of 6-96 months for endemic goiter, Hashimoto’s thyroiditis or thyroid cancer. PBMC was significantly reduced compared to controls (p L-thyroxine should be reserved for cancer patients only.

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