The product of the Drosophila gene vasa is very similar to eukaryotic initiation factor-4A
- 1 October 1988
- journal article
- Published by Springer Nature in Nature
- Vol. 335 (6191) , 611-617
- https://doi.org/10.1038/335611a0
Abstract
The vasa gene product of Drosophila melanogaster is required only in the female germ line. Progeny of females homozygous for vasa mutations lack posterior structures and pole cells. Isolation and characterization of vasa genomic and complementary DNA clones show that the transcript is abundant in the female germ line and early embryos only. The predicted amino acid sequence is very similar to those of the translation initiation factor eIF-4A and the human nuclear antigen p68.Keywords
This publication has 50 references indexed in Scilit:
- A gradient of bicoid protein in Drosophila embryosCell, 1988
- Determination of Anteroposterior Polarity in DrosophilaScience, 1987
- Isolation of Drosophila clones encoding maternally restricted RNAsDevelopmental Biology, 1987
- Maternal genes required for the anterior localization of bicoid activity in the embryo of DrosophilaGenes & Development, 1987
- Involvement of the pumilio gene in the transport of an abdominal signal in the Drosophila embryoNature, 1987
- Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene networkCell, 1986
- Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoidNature, 1986
- Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in drosophilaCell, 1986
- Maternal-effect mutations altering the anterior-posterior pattern of the Drosophila embryoWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1986
- tudor, a gene required for assembly of the germ plasm in Drosophila melanogasterCell, 1985