Kaposi’s Sarcoma in Zaire Is Not Associated with HTLV-III Infection

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To the Editor: The association between the acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma in younger men has been recognized since the beginning of the AIDS outbreak1 in 1981. Before 1981, Kaposi's sarcoma was seen in the United States only infrequently and generally in older men.2 However, other geographic areas, particularly central Africa, have a high endemic incidence of Kaposi's sarcoma.3 , 4 This observation, coupled with the recognition of cases of AIDS with opportunistic infections among Africans in Africa,5 , 6 Africans in Europe,7 , 8 and European residents of Africa,9 , 10 suggested that the causative agent of AIDS might be endemic in Africa and possibly . . .