New Alcohol Protecting Groups. β,β,β-Trichloroethoxymethyl Ethers
- 1 January 1979
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 9 (1) , 57-62
- https://doi.org/10.1080/00397917908065643
Abstract
There is a continuing need for a variety of means to selectively protect and deprotect functional groups. Several recent reports have introduced new methods for the selective protection and deprotection of hydroxyl groups.1 We wish to describe a new group, the β, β, β-trichloroethoxymethyl (TCEM) ether which we believe will prove useful in a variety of synthetic applications.Keywords
This publication has 15 references indexed in Scilit:
- Stereocontrolled route to a key intermediate for the synthesis of maytansineTetrahedron Letters, 1975
- Efficacious cleavage of the benzyl ether protecting group by electrochemical oxidationThe Journal of Organic Chemistry, 1975
- Cleavage of allyloxycarbonyl protecting group from oxygen and nitrogen under mild conditions by nickel carbonylThe Journal of Organic Chemistry, 1973
- Mono- and di-2,2,2-trichloroethyl acetals as protecting groupsThe Journal of Organic Chemistry, 1973
- Prostaglandins. X. Synthesis of prostaglandin models and prostaglandins by conjugage addition of a functionalized organocopper reagentJournal of the American Chemical Society, 1972
- Protection of hydroxyl groups as tert-butyldimethylsilyl derivativesJournal of the American Chemical Society, 1972
- 9-Anthroxy. A protecting group removable by singlet oxygen oxidationThe Journal of Organic Chemistry, 1971
- Deprotection of masked steroidal alcohols by hydride transferJournal of the Chemical Society D: Chemical Communications, 1971
- The Total Synthesis of Cephalosporin C1Journal of the American Chemical Society, 1966
- The Preparation and the Kinetics of Solvolysis of Some Derivatives of beta,beta,beta-Trichloroethanol.Acta Chemica Scandinavica, 1960