Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes
- 15 May 2004
- journal article
- Published by Elsevier in Developmental Biology
- Vol. 269 (2) , 479-488
- https://doi.org/10.1016/j.ydbio.2004.01.040
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- The PAX6 gene is activated by the basic helix–loop–helix transcription factor NeuroD/BETA2Biochemical Journal, 2003
- Cre-loxp fate-mapping ofPax6 enhancer active retinal and pancreatic progenitorsGenesis, 2002
- Paths to the pancreasNature Genetics, 2002
- Conserved Sequences in a Tissue-Specific Regulatory Region of the pdx-1 Gene Mediate Transcription in Pancreatic β Cells: Role for Hepatocyte Nuclear Factor 3β and Pax6Molecular and Cellular Biology, 2002
- Pancreatic organogenesis — developmental mechanisms and implications for therapyNature Reviews Genetics, 2002
- Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eyeGenes & Development, 2000
- Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2Nature Genetics, 1997
- Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreasNature, 1997
- The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreasNature, 1997
- Insulin-promoter-factor 1 is required for pancreas development in miceNature, 1994