Localization of the gene for human 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) to chromosome band 16q22
- 1 January 1995
- journal article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 71 (2) , 124-125
- https://doi.org/10.1159/000134089
Abstract
The enzyme 11β-hydroxysteroid dehydrogenase type 2(11βHSD2) is an NAD-dependent, high-affinity isoform that potently inactivates glucocorticoids. In the present study we have used fluorescence in situ hybridization and an 11βHSD2 cDNA isolated from human kidney as probe to localize the gene encoding 11βHSD2. The gene, which has been given the symbol HSDl 1B2, maps to human chromosome band 16q22.Keywords
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