Illicit Drug Use and Risk for USA300 Methicillin-ResistantStaphylococcus aureusInfections with Bacteremia
Open Access
- 1 September 2010
- journal article
- research article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 16 (9) , 1419-1427
- https://doi.org/10.3201/eid1609.091802
Abstract
To assess the association of illicit drug use and USA300 methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, a multicenter study was conducted at 4 Veterans Affairs medical centers during 2004–2008. The study showed that users of illicit drugs were more likely to have USA300 MRSA bacteremia (in contrast to bacteremia caused by other S. aureus strains) than were patients who did not use illicit drugs (adjusted relative risk 3.0; 95% confidence interval 1.9–4.4). The association of illicit drug use with USA300 MRSA bacteremia decreased over time (p = 0.23 for trend). Notably, the proportion of patients with USA300 MRSA bacteremia who did not use illicit drugs increased over time. This finding suggests that this strain has spread from users of illicit drugs to other populations.Keywords
This publication has 29 references indexed in Scilit:
- CDC/NHSN surveillance definition of health care–associated infection and criteria for specific types of infections in the acute care settingPublished by Elsevier ,2008
- Community-Associated Strains of Methicillin-ResistantStaphylococccus aureusas the Cause of Healthcare-Associated InfectionInfection Control & Hospital Epidemiology, 2006
- Methicillin-ResistantS. aureusInfections among Patients in the Emergency DepartmentNew England Journal of Medicine, 2006
- Comparison of Community- and Health Care–Associated Methicillin-Resistant Staphylococcus aureus InfectionJAMA, 2003
- Typing of Methicillin-Resistant Staphylococcus aureus in a University Hospital Setting by Using Novel Software for spa Repeat Determination and Database ManagementJournal of Clinical Microbiology, 2003
- Pulsed-Field Gel Electrophoresis Typing of Oxacillin-ResistantStaphylococcus aureusIsolates from the United States: Establishing a National DatabaseJournal of Clinical Microbiology, 2003
- Outbreaks of community-associated methicillin-resistant Staphylococcus aureus skin infections--Los Angeles County, California, 2002-2003.2003
- New methods to investigate infectious disease transmission and pathogenesis — Staphylococcus aureus disease in drug usersThe Lancet Infectious Diseases, 2002
- Community-Acquired Methicillin-Resistant Staphylococcus aureus in a Rural American Indian CommunityJAMA, 2001
- Pathogenic Significance of Methicillin Resistance for Patients with Staphylococcus aureus BacteremiaClinical Infectious Diseases, 2000