Graft-versus-myeloma after withdrawal of immunosuppression following allogeneic peripheral stem cell transplantation
- 1 October 1999
- journal article
- case report
- Published by Springer Nature in Bone Marrow Transplantation
- Vol. 24 (8) , 925-927
- https://doi.org/10.1038/sj.bmt.1701980
Abstract
There is growing evidence for a graft-versus-myeloma effect following allogeneic stem cell transplantation. We add to this evidence by reporting complete remission achieved by withdrawal of immunosuppression in a patient with multiple myeloma progressing after HLA-identical sibling peripheral stem cell transplantation. De novo chronic graft-versus-host disease coincided with the anti-myeloma effect and responded to treatment. The patient remains in complete remission 3 years after transplant.Keywords
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