Histamine release from rat mast cells induced by protamine sulfate and polyethylene imine
- 1 April 1981
- journal article
- Published by Springer Nature in Inflammation Research
- Vol. 11 (1-2) , 73-74
- https://doi.org/10.1007/bf01991461
Abstract
The protamine sulfate-induced release of histamine from rat mast cells is a non-cytotoxic reaction, similar to the 48/80-induced secretion. Polyethylene imine was found to be a less potent releaser. It is a cytotoxic substance without specificity for mast cells and acts on membranes generally. Although the two agents are related concerning their molecular weight and polybasicity, their mode of action on mast cells is clearly different.Keywords
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