RENAL SODIUM EXCRETORY CAPACITY IN INFANTS UNDER DIFFERENT DIETARY CONDITIONS

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Abstract
An evaluation of dietary effects on Na homeostasis was performed in 28 healthy infants 7-13 wk of age. Each infant received an ordinary formula for 1 wk in which either the Na and/or the protein content was increased 2 .times.. The high Na diets induced a significant elevation of the natriuretic response to an oral Na load. The response was most pronounced in those infants receiving a high Na and a high protein diet. The diet that was only high in protein resulted in an increased osmotic load to the kidneys but did not affect the Na excretion. The maturation of renal Na excretion was accelerated by a high Na intake and further potentiated by a high protein intake. The Na excretory capacity was, even after the period of a high Na diet, well above the level of Na given.