Abstract
Of 422 clinical strains of P. aeruginosa, 23 (5.5%) were resistant to gentamicin; 19 were also resistant to tobramycin and sisomycin; and 1 was resistant to tobramycin, sisomycin and amikacin. Of the gentamicin-resistant strains, 20 were also resistant to kanamycin. Sixteen strains with a high level of resistance to gentamicin (MIC [minimal inhibitory concentration] > 160 .mu.g/ml) transferred all their resistance determinants to recipient strains of P. aeruginosa and 4 transferred some resistance to determinants to P. aeruginosa but none transferred resistance to a recipient strain of E. coli K12. Gentamicin resistance in strains of P. aeruginosa isolated in Auckland is mediated by R plasmids.

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