cDNA cloning of a new member of the Ras superfamily, RAB9-like, on the human chromosome Xq22.1–q22.3 region
- 1 September 2000
- journal article
- research article
- Published by Springer Nature in Journal of Human Genetics
- Vol. 45 (5) , 318-322
- https://doi.org/10.1007/s100380070025
Abstract
Members of the RAB protein family regulate vesicular trafficking and reside in specific intercellular compartments. A new member of the RAB family was identified through a public database search, and its full-length cDNA was isolated from a human fetal brain cDNA library. The predicted protein product of the gene consists of 201 amino acid residues, and the protein has 86% similarity to human RAB9 at the amino acid level. We designated the new gene RAB9-like. Northern blot analysis showed that the gene was transcribed ubiquitously in various human tissues. A database search revealed that the gene is divided into three exons and spans approximately 7.2 kb of the genome DNA of chromosome Xq22.1–q22.3 region.Keywords
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