TRAUMATIC RENAL FAILURE IN THE RAT
- 1 March 1954
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 32 (2) , 86-108
- https://doi.org/10.1139/o54-011
Abstract
A systematic study of the variables connected with the production of renal damage following a crushing limb injury in the rat was made. The state of hydration of the animal immediately prior to and following the crushing injury appears to be the most critical variable. Myoglobin, while it intensifies the renal dysfunction, is not necessary for its production. Both the area involved in the crush and the amt. of renal reserve are important factors. Various steroid hormones were ineffective in altering the course of the disease.Keywords
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