Simultaneous Binding of Two Different Drugs in the Binding Pocket of the Human Multidrug Resistance P-glycoprotein
Open Access
- 1 October 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (41) , 39706-39710
- https://doi.org/10.1074/jbc.m308559200
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- RETRACTED: Structure of MsbA from Vibrio cholera: A Multidrug Resistance ABC Transporter Homolog in a Closed ConformationJournal of Molecular Biology, 2003
- Permanent Activation of the Human P-glycoprotein by Covalent Modification of a Residue in the Drug-binding SiteJournal of Biological Chemistry, 2003
- Substrate-induced Conformational Changes in the Transmembrane Segments of Human P-glycoproteinPublished by Elsevier ,2003
- Introduction of the Most Common Cystic Fibrosis Mutation (ΔF508) into Human P-glycoprotein Disrupts Packing of the Transmembrane SegmentsJournal of Biological Chemistry, 2002
- Multidrug resistance in cancer: role of ATP–dependent transportersNature Reviews Cancer, 2002
- Determining the Dimensions of the Drug-binding Domain of Human P-glycoprotein Using Thiol Cross-linking Compounds as Molecular RulersJournal of Biological Chemistry, 2001
- Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with DibromobimaneJournal of Biological Chemistry, 2000
- BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTERAnnual Review of Pharmacology and Toxicology, 1999
- Quality Control by Proteases in the Endoplasmic ReticulumJournal of Biological Chemistry, 1998
- ATPase activity of partially purified P-glycoprotein from multidrug-resistant Chinese hamster ovary cellsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1992