Effect of thyroid hormone on myocardial catecholamine content of the guinea pig
- 30 November 1961
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 201 (6) , 1049-1052
- https://doi.org/10.1152/ajplegacy.1961.201.6.1049
Abstract
Normal and thyroidectomized guinea pigs were subjected to treatment with either triiodothyronine or thyroid-stimulating hormone. Determinations of myocardial catecholamine content and serum protein-bound iodine revealed a significant increase in myocardial norepinephrine content in the markedly thyrotoxic animal, and a significant decrease in norepinephrine content of the myocardium of hypothyroid animals. The significance of these findings in defining the role of catecholamines in various states of thyroid function is discussed.Keywords
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