Reduction of blood pressure with calcium supplementation in young adults
- 4 March 1983
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 249 (9) , 1161-1165
- https://doi.org/10.1001/jama.249.9.1161
Abstract
Epidemiologic and animal studies suggest an inverse relationship between Ca intake and BP [blood pressure]. Ca intake seems to be inversely correlated with the incidence of eclampsia in pregnancy. In a randomized clinical trial, young adults were allocated to a Ca-supplemented group receiving 1 g/day of elemental C (15 men and 15 women) or a placebo group (14 women and 13 men) for a period of 22 wk. The Ca-supplemented group showed a significant decrease in diastolic BP; this effect was stabilized after 9 wk in women and 6 wk in men. The reduction in diastolic BP was 5.6% and 9% from the initial values for women and men, respectively. This study supports epidemiologic and animal evidence of the effect of Ca intake on BP and suggests the need for more research exploring the mechanisms involved in the observed effect.This publication has 2 references indexed in Scilit:
- Rise of blood pressure in calcium-deprived pregnant ratsAmerican Journal of Obstetrics and Gynecology, 1981
- Effects of Parathyroid Hormone on the Distribution and Transport of Calcium in Cultured Kidney Cells*Endocrinology, 1978