Aztreonam in the management of Gram-negative infections in penicillin-allergic patients
- 1 September 1989
- journal article
- review article
- Published by Wolters Kluwer Health in The Pediatric Infectious Disease Journal
- Vol. 8 (9) , S124-127
- https://doi.org/10.1097/00006454-198909001-00008
Abstract
Penicillins and cephalosporins, which are well-tolerated by most patients, can result in hypersensitivity reactions. This factor not only limits the use of beta-lactam antibiotics but also presents challenges to the selection of alternative drugs because of the potential for cross-reactivity. Evidence suggests that aztreonam, the prototype of the new monobactam class of beta-lactam antibiotics, may be a safe alternative antibiotic for managing Gram-negative infections in penicillin-allergic patients.Keywords
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