Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family

This publication has 18 references indexed in Scilit:

• BH3-only proteins: orchestrating cell death
  Cell Death & Differentiation, 2006
• At the gates of death
  Cancer Cell, 2006
• Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins
  Cell Death & Differentiation, 2006
• Promoting apoptosis as a strategy for cancer drug discovery
  Nature Reviews Cancer, 2005
• Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x_L, but not Bcl-2, until displaced by BH3-only proteins
  Genes & Development, 2005
• Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function
  Molecular Cell, 2005
• The Bcl-2 family: roles in cell survival and oncogenesis
  Oncogene, 2003
• The Structure of a Bcl-xL/Bim Fragment Complex
  Immunity, 2003
• Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies
  Protein Science, 2000
• Structure of Bcl-x _L -Bak Peptide Complex: Recognition Between Regulators of Apoptosis
  Science, 1997