Experimental model of oral antityphoid vaccination with live streptomycin-dependentSalmonella typhimuriumin C57BL/6 mice
- 1 October 1975
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 75 (2) , 215-218
- https://doi.org/10.1017/s0022172400047240
Abstract
The present experimental model offered the opportunity to study particular aspects concerning the avirulence stability of live streptomycin-dependent (Sm D) Salmonella vaccines, under conditions resembling human enteric fever. The results seem to indicate that, in practice, the risk of reversion to a virulent form during oral antityphoid vaccination with Sm D strains remains slight even after the interruption of concomitant streptomycin administration.Keywords
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