Formol-Saline as A Cell Conserving Medium in the Micronucleus Test
- 1 January 1986
- journal article
- other
- Published by Taylor & Francis in Stain Technology
- Vol. 61 (1) , 59-60
- https://doi.org/10.3109/10520298609110707
Abstract
It is widely recognized that tests using mammalian cell sytems are essential for assessing mutagenic hazard (Ishidate and Yoshikawa 1980). The micre nucleus test (Von Ledebur and Schmid 1973, Schmid 1973) is a convenient in vivo technique to overcome the shortcomings of in vitro bacterial methods. However, this assay requires high quality smears, for the production of which the solution used to avoid cell damage is critical.Keywords
This publication has 5 references indexed in Scilit:
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- Chromosome Aberration Tests with Chinese Hamster Cells in vitro with and without Metabolic Activation — A Comparative Study on Mutagens and CarcinogensPublished by Springer Nature ,1980
- Sodium Citrate as a Substitute for Fetal Calf Serum in the Micronucleus TestStain Technology, 1980
- The micronucleus test methodological aspectsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1973
- Chemical mutagen testing on in vivo somatic mammalian cellsInflammation Research, 1973