GROWTH HORMONE AND VITAMIN D IN RELATION TO GROWTH AND CALCIFICATION ON A CALCIUM DEFICIENT DIET1
- 1 November 1957
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 61 (5) , 590-593
- https://doi.org/10.1210/endo-61-5-590
Abstract
With rats on a low-Ca (0.015%) normal-P (0.3%) semisynthetic diet both growth hormone and vitamin D increased body weights, femur lengths, femur organic matter, and metaphyseal widths. While P balances generally increased with increase in growth, Ca loss which was decreased by vitamin D, was unaffected by growth hormone. Only vitamin D increased Ca absorption; and only vitamin D increased serum Ca and serum inorganic P. A beneficial effect of growth hormone on Ca metabolism per se was not demonstrated. With hypophysectomized rats, as compared with normal rats, the only similarity in effect of the vitamin was that it increased serum Ca in both. In these the vitamin was unable to induce growth or calcification.Keywords
This publication has 2 references indexed in Scilit:
- Calcium metabolism and growth in the rat on a low-phosphorus diet as affected by vitamin D and increases in calcium intakeArchives of Biochemistry and Biophysics, 1956
- VITAMIN-D AND CITRATURIA1952