Prevalence of the Fragile X Syndrome in an Institution for the Mentally Handicapped
- 1 June 1986
- journal article
- research article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 148 (6) , 655-657
- https://doi.org/10.1192/bjp.148.6.655
Abstract
In an investigation to find the prevalence of the fragile X (Martin Bell) syndrome in a mental handicap hospital, chromosomal investigations were carried out in 196 males selected out of a total of 512, and also in 20 female patients who were related to some of the selected males. Fragile X cells were found in 41 of the males and two of the females; in 21 of the males it was associated with macro-orchidism. The overall prevalence in the hospital for males (8.0%) ranks this syndrome next in importance to Down's syndrome as a known cause for mental handicap.This publication has 11 references indexed in Scilit:
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