Effect of a high-fat diet on the excretion of bisulphite-binding substances in the urine of rats deficient in vitamin B1
- 31 August 1940
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 34 (8-9) , 1329-1333
- https://doi.org/10.1042/bj0341329
Abstract
The ingestion of a high-fat diet by rats deprived of vit. B1 diminished the excretion of bisulphite-binding substances in their urine and alleviated the severity of the bradycardia. The aneurin-sparing action of fat, therefore, is not limited to its effect in protecting such animals against loss of wt. or the development of the better known symptoms of deficiency, but shows itself likewise in the absence of these 2 characteristic signs of the avitaminosis. The significance of these results for vit. assays, and for the assessment of deficiency, is discussed.This publication has 6 references indexed in Scilit:
- Methods for assessing the level of nutrition. A carbohydrate tolerance test for vitamin B1Biochemical Journal, 1939
- Alleviation of Vitamin B Deficiency in the Rat by Certain Natural Fats and Synthetic EstersJournal of Nutrition, 1937
- Bradycardia in the vitamin B1-deficient rat and its use in vitamin B1 determinationsBiochemical Journal, 1934
- A method of determination of some biologically important aldehydes and ketones, with special reference to pyruvic acid and methylglyoxalBiochemical Journal, 1932
- Vitamin B deficiency in the ratBiochemical Journal, 1930
- SPARING ACTION OF FAT ON THE ANTINEURITIC VITAMINScience, 1928