Multiple Sclerosis — The Plaque and Its Pathogenesis
Top Cited Papers
- 2 March 2006
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 354 (9) , 942-955
- https://doi.org/10.1056/nejmra052130
Abstract
Substantial advances have elucidated some of the central mechanisms underlying the inflammation, demyelination, and neurodegeneration that occur in multiple sclerosis. Correspondingly, the clinical strategies available for the management of the disease have widened. This review focuses on the current knowledge of the pathogenesis of the inflammatory and neurodegenerative elements of the multiple sclerosis plaque.Keywords
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