A FACILE SYNTHESIS OF CARBOXAMIDES BY USING 1-METHYL-2-HALOPYRIDINIUM IODIDES AS COUPLING REAGENTS
- 5 November 1975
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 4 (11) , 1163-1166
- https://doi.org/10.1246/cl.1975.1163
Abstract
Carboxamides are rapidly formed in high yields by equimolar reactions of free carboxylic acids and amines, involving secondary or tertiary alkyl substituted acids and amines, with 1-methyl-2-halopyridinium iodides in the presence of tri-n-butylamine.Keywords
This publication has 24 references indexed in Scilit:
- Analgesics. Some Substituted 2,3-Dihydro-4-quinolones1Journal of Medicinal Chemistry, 1965
- N-Acylation of CysteineThe Journal of Organic Chemistry, 1965
- Formylation of AminesThe Journal of Organic Chemistry, 1958
- Reaktionen an der Carbonamid‐Gruppe, II. MitteilungEuropean Journal of Inorganic Chemistry, 1953
- The Structure and Chemistry of Actidione, an Antibiotic from Streptomyces GriseusJournal of the American Chemical Society, 1949
- Amino Acids. V.1 Phthalyl DerivativesJournal of the American Chemical Society, 1948
- BENZIMIDAZOLE STUDIES. I. THE MECHANISM OF BENZIMIDAZOLE FORMATION FROM O-PHENYLENEDIAMINEThe Journal of Organic Chemistry, 1941
- THE ISOMERISM OF PHENYLPHTHALIMIDE AND A STUDY OF THE NITRO AND CHLORO DERIVATIVESJournal of the American Chemical Society, 1928
- Über Acylieren von Aminen und PhenolenEuropean Journal of Inorganic Chemistry, 1909
- Acetylirung mit Essigsäureanhydrid in wässriger LösungEuropean Journal of Inorganic Chemistry, 1900