Caspofungin Activity against Clinical Isolates of Fluconazole-Resistant Candida
- 1 December 2003
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 41 (12) , 5729-5731
- https://doi.org/10.1128/jcm.41.12.5729-5731.2003
Abstract
A total of 7,837 clinical isolates of Candida were tested against fluconazole, and 351 resistant (fluconazole MIC ≥ 64 μg/ml) isolates were identified (4% of the total tested). All fluconazole-resistant isolates were inhibited by caspofungin at concentrations that can be exceeded by standard doses (MIC at which 90% of the isolates were inhibited, 1 μg/ml; 99% of the MICs were ≤2 μg/ml).Keywords
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