Benzimidazole-Based fXa inhibitors with improved thrombin and trypsin selectivity
- 20 March 2002
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 12 (9) , 1311-1314
- https://doi.org/10.1016/s0960-894x(02)00145-2
Abstract
No abstract availableKeywords
This publication has 4 references indexed in Scilit:
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- Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsinActa Crystallographica Section D-Biological Crystallography, 1999
- Chapter 9. Anticoagulants: Thrombin and Factor Xa InhibitorsPublished by Elsevier ,1999
- Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor XaJournal of Medicinal Chemistry, 1998