The nucleotide sequence at the termini of adenovirus type 5 DNA
- 1 January 1977
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 4 (12) , 4371-4390
- https://doi.org/10.1093/nar/4.12.4371
Abstract
The sequences of the first 194 base pairs at both termini of adenovirus type 5 (Ad5) DNA have been determined, using the chemical degradation technique developed by Maxam and Gilbert (Proc. Nat. Acad. Sci. USA 74 (1977), pp. 560-564). The nucleotide sequences 1-75 were confirmed by analysis of labeled RNA transcribed from the terminal HhaI fragments in vitro. The sequence data show that Ad5 DNA has a perfect inverted terminal repetition of 103 base pairs long.Keywords
This publication has 28 references indexed in Scilit:
- Identification of a protein linked to the ends of adenovirus DNACell, 1977
- Characterization of single-stranded viral DNA sequences present during replication of adenovirus types 2 and 5Cell, 1976
- Two complementary strand-specific termination sites for adenovirus DNA replicationCell, 1976
- Evidence for palindromic sequences near the termini of adenovirus 2 DNABiochemical and Biophysical Research Communications, 1976
- Physical mapping of temperature-sensitive mutations of adenovirusesJournal of Molecular Biology, 1975
- Transcription by Escherichia coli RNA polymerase of a single-stranded fragment by bacteriophage φX174 DNA 48 residues in lengthJournal of Molecular Biology, 1975
- Direct determination of DNA nucleotide sequences: Structure of a fragment of bacteriophage φX174 DNAJournal of Molecular Biology, 1974
- Palindromic base sequences and replication of eukaryote chromosome endsNature, 1974
- Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresisBiochemistry, 1973
- Chromatography of 32P‐Labelled Oligonucleotides on Thin Layers of DEAE‐CelluloseEuropean Journal of Biochemistry, 1969